[Lfm] CoVID-19

Isabel Palacios i.palacios at qmul.ac.uk
Wed Mar 18 12:44:45 GMT 2020


a link to extracting RNA without kits

http://www.en-journal.org/journal/view.html?uid=513&vmd=Full

On 18/03/2020 12:43, Fernandes, Vilaiwan wrote:
> This too:
>
> From: Kathryn Harris <Kathryn.Harris at gosh.nhs.uk>
> Sent: 17 March 2020 09:30
> To: Vice Provost (Health) <viceprovosthealth at ucl.ac.uk>
> Subject: Request for help with coronavirus testing reagents
> Would to be possible to put the following request out across the UCL 
> network?
> If anyone is using the following master mix: ‘SuperScript III One-Step 
> RT-PCR System with Platinum Taq DNA Polymerase’ could they please 
> contact me by email. This is to help with COVID-19 testing in 
> Microbiology. Even small amounts would be potentially helpful.
> Kind Regards
> Kathryn
> Kathryn Harris PhD, FRCPath
> Principal Clinical Scientist
> Microbiology, Virology and Infection Prevention & Control
> Level 4 Camelia Botnar Laboratories
> Great Ormond Street Hospital NHS Foundation Trust
> London WC1N 3JH
> Tel: 020 7405 9200 x0437
>
> ------------------------------------------------------------------------
> *From:* Lfm <lfm-bounces at londonflymeeting.org> on behalf of Alex Gould 
> <Alex.Gould at crick.ac.uk>
> *Sent:* Wednesday, March 18, 2020 12:34:56 PM
> *To:* Manolis Fanto <manolis.fanto at kcl.ac.uk>
> *Cc:* lfm at londonflymeeting.org <lfm at londonflymeeting.org>
> *Subject:* Re: [Lfm] CoVID-19
> Hi All,
>
> Below is an extract from an email I got requesting PCR volunteers from 
> our labs on behalf of Public Health England. According to them, the 
> sample swabs will already have been sterilised.
>
> Best wishes to you all at this tricky time,
>
> Alex
>
> To that we would be grateful if you could consult with your group and 
> provide a list of any who would wish to volunteer in this way. As you 
> may imagine there are all sorts of uncertainties that remain to be 
> resolved, but the current position is broadly as follows:
>
> • The major current diagnostic bottleneck is PCR, therefore this call 
> is for those competent in PCR methods – the NHS will be operating at 
> clinical diagnostic standards and will of course provide training 
> where needed
>
> • Many Crick laboratories could probably manage some secondment of lab 
> members to diagnostic labs, so for instance a lab member could 
> volunteer for 2 sessions per week (2 x 4hr) and still keep other Crick 
> lab work going
>
> • There should not be major safety issues (virus should be sterilized 
> prior to all procedures), but those that government has defined 
> vulnerable groups should not volunteer (this would be in line with 
> directions to those groups about home working)
>
> • There are a number of NHS laboratories which have indicated a need, 
> so once we have a list of those who are interested, we will work to 
> provide the most straightforward and protected (travel and other) 
> arrangements – including compensating any expenses which you might incur
>
>
>
>> On 18 Mar 2020, at 12:27, Fanto, Manolis <manolis.fanto at kcl.ac.uk 
>> <mailto:manolis.fanto at kcl.ac.uk>> wrote:
>>
>> I do have to say that I would not feel particularly safe with having 
>> the average fly pusher manipulating swabs of potentially infective 
>> material. I’d say this has to be done with all precautions by experts 
>> in Cat2 or 3 facilities.
>> What other researchers could do is to receive isolated RNA and run 
>> pcrs, not more than this.
>> I volunteer the Crick for that😉. As far as King’s and UCL go, we are 
>> shutting down labs this week.
>> *From:*Lfm <lfm-bounces at londonflymeeting.org 
>> <mailto:lfm-bounces at londonflymeeting.org>>*On Behalf Of*Isabel Palacios
>> *Sent:*18 March 2020 12:20
>> *To:*lfm at londonflymeeting.org <mailto:lfm at londonflymeeting.org>
>> *Subject:*Re: [Lfm] CoVID-19
>>
>> i wondered myself about this, but i am not sure... what then? we 
>> should be isolating ourselves more now in any case? happy  to discuss 
>> more. i have a protocol for the rtpcr, as well as rna etxraction 
>> protocols that dont need kits
>>
>> On 18/03/2020 12:16, Stefano Casalotti wrote:
>>
>>     Dear All
>>     this email is not about flies but CoVID-19. I am writing to this
>>     forum because it is biggest forum I am in touch with.
>>     I am wondering whether like me  you are surprised about the
>>     decision of the government to do minimal testing for the virus :
>>     effectively they test only those that are ill and in hospital.
>>     WHO is urging all countries to do as much testing as possible.
>>     The scientific community would have a very large capacity  to
>>     carry out tests for the virus, and we could set up a system where
>>     members of the public could send  swabs to be tested. Of course
>>     there are very major  logistic steps to take but I think it is
>>     case of 'where there is a will there is a way’
>>     Probably this kind of thinking is happening in other online
>>     groups (please point me to them if it is the case)  but I was
>>     wondering what anybody thinks about this and whether they would
>>     be interested in forming a group prepared to take on such an
>>     initiative.
>>     Regards
>>     Stefano
>>
>>     Dr. Stefano Casalotti
>>     Honorary Senior Lecturer
>>     University of East London
>>     School Health, Sport and Bioscience
>>     Water Lane , London E15 4LZ
>>     M: +44 (0)7763300261
>>
>>
>>
>>         On 13 Mar 2020, at 11:55, Nic Tapon <Nic.Tapon at crick.ac.uk
>>         <mailto:Nic.Tapon at crick.ac.uk>> wrote:
>>         *This email is from an external source. Ensure you trust the
>>         sender before opening any attachments or clicking on any links.*
>>         ------------------------------------------------------------------------
>>         Dear LFMers,
>>         Sadly, we have taken the decision to*cancel the March and
>>         April LFM*s, which will probably not come as a surprise to
>>         all of you.
>>         We will monitor the situation and will make a decision on the
>>         May and June meetings so that we can update you as soon as
>>         possible.
>>         In the meantime, best wishes to all of you during these
>>         trying times!
>>         Kind regards,
>>         Nic, Isabel and Lucy
>>         /The Francis Crick Institute Limited is a registered charity
>>         in England and Wales no. 1140062 and a company registered in
>>         England and Wales no. 06885462, with its registered office at
>>         1 Midland Road London NW1 1AT/
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>> -- 
>> Isabel M. Palacios
>> Lecturer in Cell Biology
>> School of Biological & Chemical Sciences
>> Queen Mary University of London
>> Scientific visitor at the University of Cambridge
>> Founder of DrosAfricahttp://drosafrica.org  <https://eur01.safelinks.protection.outlook.com/?url=http%3A%2F%2Fdrosafrica.org%2F&data=02%7C01%7C%7C7f943c6c2aba4f142d6108d7cb39e747%7C569df091b01340e386eebd9cb9e25814%7C0%7C0%7C637201321885112264&sdata=eIxxbTv6FgPr4qCGyzVRjHMrwuXqO5n1KypydEicG4w%3D&reserved=0>
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> ************************
>
> Alex P. Gould PhD FMedSci,
> Senior Group Leader,
> Wellcome Trust Investigator,
> The Francis Crick Institute,
> 1 Midland Road,
> London NW1 1AT
> UK
>
> (courier deliveries: The Francis Crick Institute, 1 Brill Place, 
> London NW1 1BF. UK)
>
> Phone: +44 (0)20 37961452
>
> Lab Administrator:
> Anika Tailor
> anika.tailor at crick.ac.uk <mailto:anika.tailor at crick.ac.uk>
> Phone: +442037965330
>
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-- 
Isabel M. Palacios
Lecturer in Cell Biology
School of Biological & Chemical Sciences
Queen Mary University of London
Scientific visitor at the University of Cambridge
Founder of DrosAfrica http://drosafrica.org
BSCB Ambassador   http://bscb.org

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