[Lfm] FW: Special Seminar - Lucy O'Brien - November 19th 17:00

[Bostock, Matthew]

Dear all,

I am writing to advertise a CDB student/postdoc-organised seminar that will be taking place on the 19th November at 17:00. Dr. Lucy O’Brien will be speaking and I believe many of you may be interested. Please feel welcome to join, I have attached the advertisement email below with the zoom link.

All the best,

Matthew Bostock

PhD Candidate
Fernandes Lab
UCL Cell and Developmental Biology



Dear All,

Following a poll of CDB graduate students and postdocs, a list of desirable speakers was drawn up and we have extended an invitation to Lucy O'Brien of Stanford University https://www.stemdynamics.org/lucy-obrien<https://eur01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.stemdynamics.org%2Flucy-obrien&data=04%7C01%7C%7C62aaf604841c4606097e08d87cb945c5%7C1faf88fea9984c5b93c9210a11d9a5c2%7C0%7C0%7C637396482520996208%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&sdata=wkQ9MWOQvNWYyzi5Oto8QUl%2BSJeC1xcqMe6tnsIqgE4%3D&reserved=0>. She has been gracious enough to accept and will be delivering a seminar on the 19th November at 17:00.

Please feel welcome and make sure to attend as she is a fantastic speaker and will be talking about her fascinating research! Afterwards, students and postdocs have the opportunity to chat with her for an hour. This is a great opportunity to meet new people and interact with the speaker.

Abstract and zoom meeting link are attached below.

All the best,

Matthew and Tom



Abstract: Our organs contain multitudes of cells: Stem cells that generate new cells, new cells that are differentiating, differentiated cells that execute organ function, and dying cells that will soon be lost. What are the dynamics of this cellular life-cycle? How are cellular life-cycles coordinated at the organ-scale? How do they change in response to changing physiological demands? We explore these questions using the intestinal epithelium of the adult Drosophila midgut. The relative simplicity of this digestive organ--a tube comprising ~10,000 differentiated cells and ~2,000 stem cells--enables fine-grained analyses of population dynamics over space and time. By combining long-term, in vivo imaging with advanced genetic tools, we are investigating how cell numbers, fates, and organization are flexibly controlled at the tissue-scale. In my seminar, I will discuss recent insights into the homeostatic feedback signals that underlie cellular equilibrium and the spatiotemporal dynamics of cellular differentiation.



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