[Lfm] FW: A*STAR Studentship

Sun Apr 2 15:22:45 UTC 2023

Dear LFMers,

Please see below (and attached) an exciting fully funded PhD studentship opportunity, cross-disciplinary, combining live imaging and modelling of collective cell migration.
Please pass on to any student you think might be interested.
Application deadline:  21. April

It is also advertised here:
https://www.findaphd.com/phds/project/investigating-the-mechanisms-of-collective-cell-migration/?p154933<https://eur03.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.findaphd.com%2Fphds%2Fproject%2Finvestigating-the-mechanisms-of-collective-cell-migration%2F%3Fp154933&data=05%7C01%7C%7Ce66b1454cc454eb4a60308db320c1d49%7C4eed7807ebad415aa7a99170947f4eae%7C0%7C0%7C638158799997011042%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000%7C%7C%7C&sdata=NNgD4jEcbBeMctEsjhPQ0VSoYqMtgmiYdncaYjmndoU%3D&reserved=0>

For more information, please encourage students to contact:
Kyra Campbell<mailto:kyra.campbell at sheffield.ac.uk>, Wellcome Trust and Royal Society Sir Henry Dale Fellow
School of Biosciences, University of Sheffield
Lab webpage:
www.cellplasticity.weebly.com<https://eur03.safelinks.protection.outlook.com/?url=http%3A%2F%2Fwww.cellplasticity.weebly.com%2F&data=05%7C01%7C%7Ce66b1454cc454eb4a60308db320c1d49%7C4eed7807ebad415aa7a99170947f4eae%7C0%7C0%7C638158799997011042%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000%7C%7C%7C&sdata=bOUXdh9OSuIP%2FguHcvGVvkoaBM%2F3PHjL%2BSXMaf9szDQ%3D&reserved=0>
https://www.sheffield.ac.uk/bms/research/campbell<https://eur03.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.sheffield.ac.uk%2Fbms%2Fresearch%2Fcampbell&data=05%7C01%7C%7Ce66b1454cc454eb4a60308db320c1d49%7C4eed7807ebad415aa7a99170947f4eae%7C0%7C0%7C638158799997011042%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000%7C%7C%7C&sdata=%2B9Ia9euUyENcItYDovAlmrP%2BMwRgB1hT4ajOv14zhXw%3D&reserved=0>

PhD Project: Investigating the mechanisms of collective cell migration

Cell migration plays an important role in the normal development of multicellular organisms and also in cancer metastasis. While many kinds of individual cell movements have been characterised, we understand much less about how clusters of cells migrate in a coordinated fashion. Understanding the molecular and biophysical mechanisms of how cells migrate collectively, will likely lead to a better understanding of metastasis and the identification of novel molecular targets for therapeutic intervention.

This is a fully funded 4 year PhD studentship, where the selected student will spilt their time between 2 world class labs – Dr Kyra Campbell, School of Biosciences, University of Sheffield and Dr. Keng-Hwee Chiam, A*STAR Bioinformatics Institute, Singapore. This project will focus on using the embryonic midgut cells during early stages of development of the fruit fly, Drosophila melanogaster, as a model system. This model offers an unparalleled opportunity to image the dynamics of cell migration in vivo, on the Campbell lab’s own dedicated multiphoton confocal microscope in Sheffield. You will use the many tools available to perturb the system, including fine-tuned laser ablation techniques to probe and dissect the underlying forces.

As cell migration is a physical process, it is important to consider the physical aspects, such as understanding how these forces are produced and transduced. Therefore, you will spend half of your time in the lab of Dr. Chiam in the Bioinformatics Institute in Singapore, where you will develop image analysis algorithms to measure cell behaviours from the live imaging data obtained in during your first year. These data will then be used to build physical models to computationally explore different assumptions about collective cell migration and generate testable mechanistic hypotheses.

This is a unique opportunity for you to carry out cutting-edge microscopy and modelling, developing both wet lab and computational skills in exciting multidisciplinary environments.

Award details

For each student admitted to the 4-year programme, A*Star will provide the following financial support, whilst the student is in Singapore:

  *   Monthly stipend of S$2,700
  *   Monthly housing allowance of S$600
  *   One-time airfare grant of S$1,500
  *   One-time settling-in allowance of S$1,000
  *   One-time IT allowance of S$800
  *   Medical insurance
  *   Conference allowance

Whilst in Sheffield, students receive fees and stipend at the UKRI rate. Currently these are £4,596 fees and £17,668 stipend per annum. Candidates MUST qualify for home fee status

Please contact Dr. Kyra Campbell: kyra.campbell at sheffield.ac.uk<mailto:kyra.campbell at sheffield.ac.uk> for more details.

[cid:image002.jpg at 01D9657F.5ADE7280]

--
Kyra Campbell
Wellcome Trust and Royal Society Sir Henry Dale Fellow

School of Biosciences
University of Sheffield
Western Bank
Sheffield
S10 2TN
UK

Tel: +44 (0) 114 222 4690
Lab webpage:
www.cellplasticity.weebly.com<https://eur03.safelinks.protection.outlook.com/?url=http%3A%2F%2Fwww.cellplasticity.weebly.com%2F&data=05%7C01%7C%7Ce66b1454cc454eb4a60308db320c1d49%7C4eed7807ebad415aa7a99170947f4eae%7C0%7C0%7C638158799997011042%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000%7C%7C%7C&sdata=bOUXdh9OSuIP%2FguHcvGVvkoaBM%2F3PHjL%2BSXMaf9szDQ%3D&reserved=0>
https://www.sheffield.ac.uk/bms/research/campbell<https://eur03.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.sheffield.ac.uk%2Fbms%2Fresearch%2Fcampbell&data=05%7C01%7C%7Ce66b1454cc454eb4a60308db320c1d49%7C4eed7807ebad415aa7a99170947f4eae%7C0%7C0%7C638158799997323466%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000%7C%7C%7C&sdata=Zmk4wiIvw1Y3BGRUrXQOTjvvigbOLJp5db%2BmMkVTiDQ%3D&reserved=0>

The Francis Crick Institute Limited is a registered charity in England and Wales no. 1140062 and a company registered in England and Wales no. 06885462, with its registered office at 1 Midland Road London NW1 1AT
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