[Lfm] Fly request

[Jason Somers]

Hello,

I have a request from a colleague in Nigeria for fly strains that are used to model neurological diseases.

These are some that he has requested if anyone has them in stock and cares to share a flip?

S/N
Disorder
Fly Strain
Reference

1.
Schizophrenia
Rim
Hidalgo, S., Campusano, J. M., & Hodge, J. J. L. (2021). The Drosophila ortholog of the schizophrenia-associated CACNA1A and CACNA1B voltage-gated calcium channels regulate memory, sleep and circadian rhythms. Neurobiology of Disease, 155, 105394. https://doi.org/10.1016/j.nbd.2021.105394

https://www.sciencedaily.com/releases/2021/05/210519120720.htm

2.
cacophony
(CACNA1A and CACNA1B)

3.
Dysbindin (DTNBP1)
O’Kane, C. J. (2011). Drosophila as a Model Organism for the Study of Neuropsychiatric Disorders. In J. J. Hagan (Ed.), Molecular and Functional Models in Neuropsychiatry (Vol. 7, pp. 37–60). Springer Berlin Heidelberg. https://doi.org/10.1007/7854_2010_110

4.
ADHD
Radish
van der Voet, M., Harich, B., Franke, B., & Schenck, A. (2016). ADHD-associated dopamine transporter, latrophilin and neurofibromin share a dopamine-related locomotor signature in Drosophila. Molecular Psychiatry, 21(4), Article 4. https://doi.org/10.1038/mp.2015.55

5.
SLC6A3

6.
Epilepsy
parabss1
Dare, S. S., Merlo, E., Rodriguez Curt, J., Ekanem, P. E., Hu, N., & Berni, J. (2021). Drosophila parabss Flies as a Screening Model for Traditional Medicine: Anticonvulsant Effects of Annona senegalensis. Frontiers in Neurology, 11, 606919. https://doi.org/10.3389/fneur.2020.606919
Fischer, F. P., Karge, R. A., Weber, Y. G., Koch, H., Wolking, S., & Voigt, A. (2023). Drosophila melanogaster as a versatile model organism to study genetic epilepsies: An overview. Frontiers in Molecular Neuroscience, 16.https://www.frontiersin.org/articles/10.3389/fnmol.2023.1116000

7.
Parkinson’s
α-Syn-WT
Xiong, Y., & Yu, J. (2018). Modeling Parkinson’s Disease in Drosophila: What Have We Learned for Dominant Traits? Frontiers in Neurology, 9, 228. https://doi.org/10.3389/fneur.2018.00228

8.
dLRRK

9.
Alzheimer’s
Aβ42
Kasanin, J., Wang, X., Jiao, W., Li, Q., & Lu, B. (2022). Studying Alzheimer’s Disease Using Drosophila melanogaster as a Powerful Tool. Advances in Alzheimer’s Disease, 11(3), Article 3. https://doi.org/10.4236/aad.2022.113003

Cheers,

Jason Somers, PhD
Senior Laboratory Research Scientist
Neural Circuits and Evolution
The Francis Crick Institute
1 Midland Road, Rm L3-2231 SW332
London NW1 1AT


The Francis Crick Institute Limited is a registered charity in England and Wales no. 1140062 and a company registered in England and Wales no. 06885462, with its registered office at 1 Midland Road London NW1 1AT
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